nQuery Advisor (Standalone Installation) 7.0

nQuery Advisor (Standalone Installation) by Statistical Solutions Ltd is a desktop application for designing clinical trials and research studies through rigorous sample size and power analysis. Installed locally on a Windows PC with no server components, it is well suited to secure, offline, or restricted environments where standalone use is required.

Key capabilities

• Comprehensive library of validated sample size and power calculators for fixed-sample designs across continuous, binary, and time-to-event endpoints
• Support for superiority, non-inferiority, and equivalence hypotheses in parallel-group, crossover, and other common designs
• Methods for survival analysis (e.g., log-rank/Cox), means and proportions (t-tests, ANOVA/ANCOVA, chi-square), correlations, and selected repeated or clustered designs
• Step-by-step worksheet templates with clearly documented formulas, references, and assumptions
• Sensitivity analyses and power curves to explore design trade-offs and justify assumptions
• Easy export of results and tables for inclusion in protocols, statistical analysis plans, and reports

Benefits

• Produces defensible, transparent sample size justifications for regulatory and stakeholder review
• Reduces the risk of underpowered or overpowered studies by enabling rapid “what-if” exploration
• Streamlines protocol development with reproducible outputs and clear methodological citations

Typical users

• Biostatisticians, clinical trial designers, medical device and pharmaceutical researchers, academic investigators, and CROs

Notes

• The Advisor edition focuses on fixed-sample designs; organizations that require group sequential or adaptive design planning typically use the Advanced modules of nQuery alongside Advisor
• Licensing and system requirements may vary by version; consult Statistical Solutions Ltd for details

nQuery Advisor (Standalone Installation) is developed by Statistical Solutions Ltd. The most popular versions of this product among our users are: 5.0 and 7.0.